FOXO4 (fork-head box O4) is a fork-head DNA-binding domain containing protein and functions as a transcription factor involved in the regulation of the insulin signaling pathway. FOXO4 binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It also down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes, and is involved in the negative regulation of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P98177].
Alternative names for
FOXO4 Antibody include
forkhead box O4 antibody,
Forkhead box protein O4 antibody,
Fork head domain transcription factor AFX1 antibody,
forkhead box protein O4 antibody,
fork head domain transcription factor AFX1 antibody,
myeloid/lymphoid or mixed-lineage leukemiatrithorax homolog, Drosophila); translocated to, 7 antibody.