FLRF/RNF41 Antibody

FLRF/RNF41 is also known as the E3 ubiquitin-protein ligase NRDP1. FLRF/RNF41 is responsible for the ubiquitination and proteasomal degradation of the EGF (epidermal growth factor) receptor family member, ErbB3/HER3. The overexpression of FLRF/RNF41 results in a decrease of ErbB3 and inhibition of breast cancer cell growth while decreased levels of FLRF/RNF41 are inversely correlated with ErbB3 levels in primary human breast cancer tissue. FLRF/RNF41 has also been shown to catalyze the degradation of BRUCE/apollon, an inhibitor of apoptosis protein (IAP).
    Product Specifications
    Catalog # Size Price
    FLRF/RNF41 AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 250 and 300
    A300-048A100 µl (1 mg/ml) $339Add to Cart
    A300-048A-M100 µl (10 blots) $229Add to Cart
    A300-048A-T20 µl (2 blots) $50Add to Cart
    FLRF/RNF41 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 275 and C-term
    A300-049A100 µl (1 mg/ml) $339Add to Cart
    Out of stock - Expected Release mid July 2015 (Updated 05/27/2015)
    FLRF/RNF41 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 275 and C-term
    IHC-00114100 µl (50+ slides) $360Add to Cart
    IHC-00114-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, IHC-P, IF, PLA
    Reactivity: Human, Mouse
    Includes: 1 each of A300-048A and A300-049A
    A310-012A1 Pack $472Add to Cart

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