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FIP200/RB1CC1
FIP200/RB1CC1 Antibody
FIP200 (FAK-family interacting protein of 200 kDa) appears to play several key roles related to cell growth, proliferation, development, and tumorigenesis. FIP200 was originally identified in a yeast two-hybrid screen for Pyk2 kinase interacting proteins. It was later identified as a protein that interacts with FAK (focal adhesion kinase), a signal transducing protein that mediates signals from the extracellular matrix to the cytoskeleton to influence cell motility, and cell cycle progression. FIP200 is also known as RB1CC1 (RB1-inducible coiled-coil 1) and has been found to function as a regulator of the retinoblastoma 1 (RB1) tumor suppressor. FIP200 associates with the tumor suppressor TSC1 which partners with TSC2 to antagonize the mTOR signaling pathway. FIP200 association with TSC2 promotes mTOR activity by interfering with the antagonistic effects of the TSC1-TSC2 complex. Alternate names for FIP200 include RBICC, CC1, and DRAGOU14.
Product / Catalog #
Specifications
Price
FIP200/RB1CC1 Antibody
A301-536A
Applications:
WB, IP
Reactivity:
Human
Quantity:
0.1 ml (20 - 100 blots)
$280.00
Data Sheet
Add to Cart
FIP200/RB1CC1 Antibody
A301-574A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
FIP200/RB1CC1 Antibody AbVantage™ Pack
A310-558A
Applications:
WB, IP
Reactivity:
Human
Quantity:
1 each of A301-536A and A301-574A
$390.00
Data Sheet
Add to Cart
FIP200/RB1CC1 Blocking Peptide
BP301-536
Applications:
Blocks A301-536A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
FIP200/RB1CC1 Blocking Peptide
BP301-574
Applications:
Blocks A301-574A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
Product Focuses
ATM and ATR Signaling Proteins
Condensin Complex
GTPase Regulation
mTOR Signaling Pathway
NFKB
Nucleoporin
SWI/SNF
USP
WD-repeat
Xeroderma Pigmentosum
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Bethyl Laboratories, Inc.
P.O. Box 850
Montgomery, TX 77356
Phone: 1-800-338-9579
Fax: 1-866-597-6105