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A-Z / FIP1
 

FIP1 Antibody

 
FIP1 was originally identified as Rhe (rearranged in hypereosinophilia) and part of a fusion protein encoded by a genetic rearrangement between the N-terminal region of FIP1 (Rhe) and the C-terminal region of the platelet-derived growth factor receptor alpha (PDGFRalpha). The fusion protein exhibits aberrant tyrosine kinase activity and is associated with hypereosinophilic syndrome (HES), a rare hematologic disorder characterized by an overproduction of eosinophils that results in organ damage. FIP1 was also identified as FIP1-like 1 in a database search for a human homolog of the yeast Fip1p (factor interacting with PAP), a subunit of the yeast 3’-end processing complex, CPF (cleavage and polyadenylation factor). Human FIP1 was similarly found to interact with PAP and CPSF160 as part of the human CPSF (cleavage and polyadenylation specificity factor) complex. In association with CPSF160, FIP1 is able to recognize U-rich elements on pre-mRNA and stimulate PAP activity. Alternate names for FIP1 include pre-mRNA 3’-end processing factor FIP1, FIP1-like 1, hFip1, and RHE.
 
Product / Catalog #SpecificationsPrice
FIP1 Antibody
A301-461A		Applications: WB, IP
Reactivity: Human
Quantity: 0.1 ml (20 - 100 blots)
$280.00
Data Sheet
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FIP1 Antibody
A301-462A		Applications: WB, IP
Reactivity: Human
Quantity: 0.1 ml (20 - 100 blots)
$280.00
Data Sheet
Add to Cart
FIP1 Antibody AbVantage™ Pack
A310-509A		Applications: WB, IP
Reactivity: Human
Quantity: 1 each of A301-461A and A301-462A
$390.00
Data Sheet
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FIP1 IHC Antibody
IHC-00293		Applications: IHC, IHC-IF
Reactivity: Human
Quantity: 0.1 ml (50 - 250 slides)
$360.00
Data Sheet
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FIP1 Blocking Peptide
BP301-461		Applications: Blocks A301-461A
Quantity: 50 mcg
$115.00
Data Sheet
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FIP1 Blocking Peptide
BP301-462		Applications: Blocks A301-462A
Quantity: 50 mcg
$115.00
Data Sheet
Add to Cart
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Bethyl Laboratories, Inc. P.O. Box 850 Montgomery, TX 77356
Phone: 1-800-338-9579 Fax: 1-866-597-6105