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FBW7
FBW7 Antibody
FBW7 (F-box and WD repeat domain containing 7) is a member of the F-box family of proteins. The F-box is a protein-protein interaction motif first identified in cyclin F. F-box proteins associate with SCFs (Skp1-cullin-F-box protein ligase complexes) which are E3 ligases that ubiquitinate proteins and target them for proteasomal degradation. FBW7 has been found to bind and specifically target cyclin E and the Notch intracellular domain (NICD) for ubiquitination. Defects in FBW7 may contribute to tumorigenesis. Alternate names for FBW7 include F-box protein FBX30, hCdc4, archipelago homolog, hAgo, SEL-10, FBXW7, and FBXO30.
Product / Catalog #
Specifications
Price
FBW7 Antibody
A301-720A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
FBW7 Antibody
A301-721A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
FBW7 Antibody AbVantage™ Pack
A310-612A
Applications:
IP
Reactivity:
Human
Quantity:
1 each of A301-720A and A301-721A
$390.00
Data Sheet
Add to Cart
FBW7 IHC Antibody
IHC-00348
Applications:
IHC, IHC-IF
Reactivity:
Human
Quantity:
0.1 ml (50 - 250 slides)
$360.00
Data Sheet
Add to Cart
FBW7 Blocking Peptide
BP301-720
Applications:
Blocks A301-720A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
FBW7 Blocking Peptide
BP301-721
Applications:
Blocks A301-721A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
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Montgomery, TX 77356
Phone: 1-800-338-9579
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