FBW7 Antibody

FBW7 (F-box and WD repeat domain containing 7) is a member of the F-box family of proteins. The F-box is a protein-protein interaction motif first identified in cyclin F. F-box proteins associate with SCFs (Skp1-cullin-F-box protein ligase complexes) which are E3 ligases that ubiquitinate proteins and target them for proteasomal degradation. FBW7 has been found to bind and specifically target cyclin E and the Notch intracellular domain (NICD) for ubiquitination. Defects in FBW7 may contribute to tumorigenesis.
    Product Specifications
    Catalog # Size Price
    FBW7 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1 and 50
    A301-720A100 µl (1 mg/ml) $339Add to Cart
    A301-720A-T10 µl (1 mg/ml) $50Add to Cart
    FBW7 AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 50 and 100
    A301-721A100 µl (1 mg/ml) $339Add to Cart
    A301-721A-T10 µl (1 mg/ml) $50Add to Cart
    FBW7 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 50 and 100
    IHC-00348100 µl (50 slides) $360Add to Cart
    Applications: IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A301-720A and A301-721A
    A310-612A1 Pack $472Add to Cart

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