FAS Antibody

Tumor necrosis factor receptor superfamily member 6, FAS, functions as the receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated FAS receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) which mediate apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P25445].
    Product Specifications
    Catalog # Size Price
    FAS AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 285 and 335
    A302-858A100 µl (1 mg/ml) $339Add to Cart
    A302-858A-M100 µl (10 blots) $229Add to Cart
    A302-858A-T20 µl (2 blots) $50Add to Cart

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