Exonuclease 1 Antibody

Exonuclease 1 is a 5'-3' double-stranded DNA exonuclease which may also possess a cryptic 3'-5' double-stranded DNA exonuclease activity. Exonuclease 1 functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. It also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Exonuclease 1 is required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes and is essential for male and female meiosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UQ84]
    Product Specifications
    Catalog # Size Price
    Exonuclease 1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 725 and 775
    A302-639A100 µl (1 mg/ml) $339Add to Cart
    A302-639A-M100 µl (10 blots) $229Add to Cart
    A302-639A-T20 µl (2 blots) $50Add to Cart
    Exonuclease 1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 796 and 846
    A302-640A100 µl (0.2 mg/ml) $339Add to Cart
    A302-640A-M100 µl (10 blots) $229Add to Cart
    A302-640A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A302-639A and A302-640A
    A310-963A1 Pack $472Add to Cart

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