ErbB2 Antibody

ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor; EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain and a cytoplasmic tyrosine-kinase domain. The epidermal growth factor (EGF) and its related proteins serve as the ligands for the ErbB receptors. Upon binding, the receptors heterodimerize, autophosphorylate and make contact with adapter molecules to transmit cellular signals involved in cell proliferation, survival, and differentiation. The ErbB2 receptor is the only member that does not interact with a ligand, but instead functions as a heterodimeric partner to coordinate signals from other ligand bound ErbB receptors. Amplification and/or overexpression of ErbB2 have been reported in many cancers.
    Product/Catalog #SpecificationsPrice
    ErbB2 Antibody
    A300-621A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    ErbB2 Antibody
    A300-622A
    Reactivity: Human
    100% Sequence Identity:
    Applications: WB, IP, IHC-P, IF
    $314.00
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    ErbB2 Antibody
    A300-623A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF, PLA
    $314.00
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    ErbB2 Antibody AbVantage™ Pack
    A310-183A
    Applications: WB, IP, IHC-P, IF, PLA
    Reactivity: Human
    Quantity: 1 each of A300-621A, A300-622A and A300-623A
    $655.00
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    ErbB2 IHC Antibody
    IHC-00032
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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