EphA2 Antibody

Ephrin type-A receptor 2 (EphA2) is a member of the Eph family of tyrosine kinase receptors. Eph receptors have been shown to play a critical role in the development of the nervous system, where they regulate patterning during neural development. The ligands for Eph receptors are ephrins. Ephrin receptors and ligands have been found to be frequently overexpressed in a wide variety of cancers. Contrary to the usual finding that the oncogenic properties of tyrosine kinase receptors are promoted by the autophosphorylation of the receptor, it is the dephosphorylation of EphA2 that is associated with its oncogenic activity. The major study of EphA2 has been in relation to its contribution to malignancy and the possibility of targeting it in cancer therapy.
    Product Specifications
    Catalog # Size Price
    EphA2 AntibodyReactivity: Human
    Applications: WB, IHC-P, IF
    Immunogen: Between 150 and 200
    A302-024A100 µl (0.2 mg/ml) $339Add to Cart
    A302-024A-M100 µl (10 blots) $229Add to Cart
    A302-024A-T20 µl (2 blots) $50Add to Cart
    EphA2 AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 926 and 976
    A302-025A100 µl (0.2 mg/ml) $339Add to Cart
    A302-025A-M100 µl (10 blots) $229Add to Cart
    A302-025A-T20 µl (2 blots) $50Add to Cart
    EphA2 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 150 and 200
    IHC-00427100 µl (50+ slides) $360Add to Cart
    IHC-00427-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A302-024A and A302-025A
    A310-714A1 Pack $472Add to Cart

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