EVI5 Antibody

The EVI5 oncogene has been identified as a protein that is localized to the centrosome and mitotic spindle, and in association with the aurora B complex, facilitates cytokinesis. EVI5 also appears to prevent premature APC/C activation and mitotic progression by stabilizing the anaphase-promoting complex/cyclosome (APC/C) inhibitor, Emi1, as well as cyclin A. EVI5 has also been demonstrated to be a binding partner of the Rab11 GTPase that regulates intracellular transport and cytokinesis.

Alternative names for EVI5 Antibody include ecotropic viral integration site 5 protein homolog antibody, EV-I5 antibody, neuroblastoma stage 4S gene antibody, NB4S antibody.