ERCC4/XPF Antibody

XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly.
    Product/Catalog #SpecificationsPrice
    XPF/ERCC4 Antibody
    A301-315A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    XPF/ERCC4 IHC Antibody
    IHC-00263
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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