ERCC4/XPF Antibody

XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly.
    Product Specifications
    Catalog # Size Price
    XPF/ERCC4 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 855 and 905
    A301-315A100 µl (0.2 mg/ml) $339Add to Cart
    A301-315A-M100 µl (10 blots) $229Add to Cart
    A301-315A-T20 µl (2 blots) $50Add to Cart
    XPF/ERCC4 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 855 and 905
    IHC-00263100 µl (50+ slides) $360Add to Cart
    IHC-00263-T10 µl (5+ slides) $50Add to Cart

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