EPC1 Antibody

Enhancer of polycomb homolog 1 (EPC1) is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H2F5 ]
    Product Specifications
    Catalog # Size Price
    EPC1 AntibodyReactivity: Human
    Applications: WB, IP, PLA
    Immunogen: Between 325 and 375
    A303-110A100 µl (1 mg/ml) $339Add to Cart
    A303-110A-M100 µl (10 blots) $229Add to Cart
    A303-110A-T20 µl (2 blots) $50Add to Cart

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