EFTUD2/SNRP116 Antibody

The splicesome is the molecular machine responsible for catalyzing intron removal from pre-mRNA transcripts. The splicesome is composed of several small nuclear RNAs (snRNAs) complexed with their associated proteins [together termed snRNPs (small nuclear ribonucleoprotein)]. One of the major classes of snRNPs includes the U1, U2, U4, U5 and U6 snRNP. EFTUD2/SNRP116 is a component of the U5 snRNP. EFTUD2/SNRP116 is a GTPase that may play a role in disrupting U4/U6 helices prior to splicesome activation.

Alternative names for EFTUD2/SNRP116 Antibody include 116 kDa U5 small nuclear ribonucleoprotein component antibody, U5 antibody, snRNP-specific protein 116 kDa antibody, U5-116 kDa antibody, elongation factor Tu GTP-binding domain protein 2 antibody, hSNU114 antibody, KIAA0031 antibody, FLJ44695 antibody, DKFZp686E24196 antibody.