The splicesome is the molecular machine responsible for catalyzing intron removal from pre-mRNA transcripts. The splicesome is composed of several small nuclear RNAs (snRNAs) complexed with their associated proteins [together termed snRNPs (small nuclear ribonucleoprotein)]. One of the major classes of snRNPs includes the U1, U2, U4, U5 and U6 snRNP. EFTUD2/SNRP116 is a component of the U5 snRNP. EFTUD2/SNRP116 is a GTPase that may play a role in disrupting U4/U6 helices prior to splicesome activation.
Alternative names for
EFTUD2/SNRP116 Antibody include SNU114 homolog antibody,
U5-116 kDa antibody,
SNU114 homolog antibody,
116 kDa U5 small nuclear ribonucleoprotein component antibody,
Elongation factor Tu GTP-binding domain-containing protein 2 antibody,
U5 snRNP-specific protein, 116 kDa antibody,
elongation factor Tu GTP binding domain containing 2 antibody,
elongation factor Tu GTP-binding domain-containing protein 2 antibody.