E2F8 Antibody

E2F8 along with E2F7, functions as an inhibitor of E2F-dependent transcription. E2F8 binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. E2F8 appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96AV8]
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