Drp1 Antibody

Dynamin-related protein 1 (Drp1) functions in mitochondrial and peroxisomal division. Drp1 mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Drp1 is required for normal brain development and facilitates developmentally-regulated apoptosis during neural tube development. Drp1 is also required for a normal rate of cytochrome c release and caspase activation during apoptosis and for mitochondrial fission during mitosis. Drp1 may be involved in vesicle transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O00429].
    Product Specifications
    Catalog # Size Price
    Drp1 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 686 and 736
    A303-410A100 µl (1 mg/ml) $339Add to Cart
    A303-410A-M100 µl (10 blots) $229Add to Cart
    A303-410A-T20 µl (2 blots) $50Add to Cart

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