Drosha Antibody

Drosha is one of three human RNase III enzymes (Drosha, Dicer, and Argonaute) that play a diverse role in the processing and maturation of RNA. Drosha, along with DGCR8 (DeGeorge Syndrome Chromomsomal Region 8, also known as Pasha in C. elegans and D. melanogaster) is a component of the Microprocessor complex. In this complex, Drosha functions as a double-stranded endoribonuclease critical to the first step in the processing of human microRNAs. During this step, Drosha is responsible for cleaving pri-miRNA to yield hairpin-shaped pre-miRNA for futher processing by the cytoplasmic RNase III enzyme, Dicer.
    Product Specifications
    Catalog # Size Price
    Drosha AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1324 and 1374
    A301-886A100 µl (0.2 mg/ml) $339Add to Cart
    Out of stock - Expected release Late February 2015 (Updated 01/31/2015)
    Drosha IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    IHC-00389100 µl (50 slides) $360Add to Cart

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