Dorfin Antibody

Dorfin is an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Dorfin specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.uniprot.org/uniprot/Q9NV58].
    Product Specifications
    Catalog # Size Price
    Dorfin AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 600 and 650
    A303-105A100 µl (1 mg/ml) $339Add to Cart
    A303-105A-T10 µl (1 mg/ml) $50Add to Cart

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