DR1 (Down-Regulator of Transcription 1) is one of two subunits (DR1 and Drap1) that make up the NC2 (Negative Co-factor 2) complex. Via it association with TATA-binding protein, NC2 functions as a regulator of transcription. In the NC2 complex DR1 is proposed to be responsible for the repressive activities of NC2.
Alternative names for
DR1 Antibody include NC2-beta antibody.