DHX36 Antibody

DHX36 is a member of the DEAH box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DHX36 expression is highest in testis and plays a role in 3’-5’ degradation of AU-rich RNAs. Interestingly, DHX36 has also been observed to function as a G4-DNA resolvase. In this capacity DHX36 catalyzes the resolution of highly stable G4- DNA structures that form in guanine-rich regions of single-stranded DNA.
    Product Specifications
    Catalog # Size Price
    DHX36 AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 950 and C-term
    A300-525A100 µl (1 mg/ml) $339Add to Cart
    A300-525A-M100 µl (10 blots) $229Add to Cart
    A300-525A-T20 µl (2 blots) $50Add to Cart

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