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DGCR8 Antibody

DiGeorge syndrome critical region 8 (DGCR8) is a component of the microprocessor complex that acts as a RNA- and heme-binding protein and is involved in the initial step of microRNA (miRNA) biogenesis. DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junctions. It directs RNASEN/DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Alternative names for DGCR8 include gy1, DGCRK6 and C22orf12. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYQ5]

Product / Catalog #	Specifications	Price
DGCR8 Antibody A302-468A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (20 - 100 blots)	$280.00 Data Sheet Add to Cart
DGCR8 Antibody A302-469A	Applications: IP Reactivity: Human Quantity: 0.1 ml	$280.00 Data Sheet Add to Cart
DGCR8 Antibody AbVantage™ Pack A310-897A	Applications: WB, IP Reactivity: Human Quantity: 1 each of A302-468A and A302-469A	$390.00 Data Sheet Add to Cart
DGCR8 Blocking Peptide BP302-468	Applications: Blocks A302-468A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart
DGCR8 Blocking Peptide BP302-469	Applications: Blocks A302-469A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart

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