DGCR8 Antibody

DiGeorge syndrome critical region 8 (DGCR8) is a component of the microprocessor complex that acts as a RNA- and heme-binding protein and is involved in the initial step of microRNA (miRNA) biogenesis. DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junctions. It directs RNASEN/DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYQ5].
    Product/Catalog #SpecificationsPrice
    DGCR8 Antibody
    A302-468A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    DGCR8 Antibody
    A302-469A
    Reactivity: Human
    Applications: IP, IHC-P, IF
    $314.00
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    Data Sheet
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    DGCR8 Antibody AbVantage™ Pack
    A310-897A
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Quantity: 1 each of A302-468A and A302-469A
    $437.00
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    DGCR8 IHC Antibody
    IHC-00688
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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