DGCR8 Antibody

DiGeorge syndrome critical region 8 (DGCR8) is a component of the microprocessor complex that acts as a RNA- and heme-binding protein and is involved in the initial step of microRNA (miRNA) biogenesis. DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junctions. It directs RNASEN/DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYQ5].
    Product Specifications
    Catalog # Size Price
    DGCR8 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 1 and 50
    A302-468A100 µl (0.2 mg/ml) $339Add to Cart
    A302-468A-M100 µl (10 blots) $229Add to Cart
    A302-468A-T20 µl (2 blots) $50Add to Cart
    DGCR8 AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 400 and 450
    A302-469A100 µl (1 mg/ml) $339Add to Cart
    A302-469A-T10 µl (1 mg/ml) $50Add to Cart

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