DDX5 Antibody

DDX5 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to a role involved in RNA splicing, DDX5 has been observed to interact with and act as a transcriptional coactivator for estrogen receptor alpha (ERalpha). DDX5 has also been found to interact with CBP/300, Smad3, and p53 to modulate transcription. DDX5 is closely related to and forms heterodimers with DDX17.
    Product Specifications
    Catalog # Size Price
    DDX5 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 550 and 600
    A300-522A100 µl (0.2 mg/ml) $339Add to Cart
    A300-522A-M100 µl (10 blots) $229Add to Cart
    A300-522A-T20 µl (2 blots) $50Add to Cart
    DDX5 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 575 and C-term
    A300-523A100 µl (0.2 mg/ml) $339Add to Cart
    A300-523A-M100 µl (10 blots) $229Add to Cart
    A300-523A-T20 µl (2 blots) $50Add to Cart
    DDX5 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 575 and C-term
    IHC-00156100 µl (50 slides) $360Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A300-522A and A300-523A
    A310-149A1 Pack $472Add to Cart

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