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DDX3 Antibody

DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions. DDX3 is also known as ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal, helicase-like protein 2, HLP2, DEAD box X isoform, DDX3X, DBX, and DDX14.

Product / Catalog #	Specifications	Price
DDX3 Antibody A300-474A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (10 - 100 blots)	$280.00 Data Sheet Add to Cart
DDX3 Antibody A300-475A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (50 - 150 blots)	$280.00 Data Sheet Add to Cart
DDX3 Antibody A300-476A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (50 - 150 blots)	$280.00 Data Sheet Add to Cart
DDX3 Antibody AbVantage™ Pack A310-136A	Applications: WB, IP Reactivity: Human Quantity: 1 each of A300-474A, A300-475A and A300-476A	$585.00 Data Sheet Add to Cart
DDX3 IHC Antibody IHC-00431	Applications: IHC Reactivity: Human, Mouse Quantity: 0.1 ml (50 - 250 slides)	$360.00 Data Sheet Add to Cart
DDX3 Blocking Peptide BP300-474	Applications: Blocks A300-474A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart
DDX3 Blocking Peptide BP300-475	Applications: Blocks A300-475A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart
DDX3 Blocking Peptide BP300-476	Applications: Blocks A300-476A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart

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