DDX3 Antibody

DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions.
    Product Specifications
    Catalog # Size Price
    DDX3 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 1 and 50
    A300-474A100 µl (0.2 mg/ml) $339Add to Cart
    A300-474A-M100 µl (10 blots) $229Add to Cart
    A300-474A-T20 µl (2 blots) $50Add to Cart
    DDX3 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 550 and 600
    A300-475A100 µl (1 mg/ml) $339Add to Cart
    A300-475A-M100 µl (10 blots) $229Add to Cart
    A300-475A-T20 µl (2 blots) $50Add to Cart
    DDX3 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 600 and C-term
    A300-476A100 µl (1 mg/ml) $339Add to Cart
    A300-476A-M100 µl (10 blots) $229Add to Cart
    A300-476A-T20 µl (2 blots) $50Add to Cart
    DDX3 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 1 and 50
    IHC-00431100 µl (50 slides) $360Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A300-474A, A300-475A and A300-476A
    A310-136A1 Pack $707Add to Cart

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