DDX3 Antibody

DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions.
    Product/Catalog #SpecificationsPrice
    DDX3 Antibody
    A300-474A
    Reactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    $314.00
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    DDX3 Antibody
    A300-475A
    Reactivity: Human
    Applications: WB, IP
    $314.00
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    DDX3 Antibody
    A300-476A
    Reactivity: Human
    Applications: WB, IP
    $314.00
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    Data Sheet
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    DDX3 Antibody AbVantage™ Pack
    A310-136A
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Quantity: 1 each of A300-474A, A300-475A and A300-476A
    $655.00
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    DDX3 IHC Antibody
    IHC-00431
    Applications: IHC-P, IF
    Reactivity: Human, Mouse
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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