DDX17 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to a role involved in RNA splicing, DDX17 has been observed to interact with and act as a transcriptional coactivator for estrogen receptor alpha (ERalpha). DDX17 is closely related to and forms heterodimers with DDX5.
Alternative names for
DDX17 Antibody include
Probable ATP-dependent RNA helicase
DEAD box protein 17 antibody,
DEAD box protein p72 antibody,
RNA-dependent helicase p72 antibody,
DEADAsp-Glu-Ala-Asp) box helicase 17 antibody,
probable ATP-dependent RNA helicase
DEADAsp-Glu-Ala-Asp) box polypeptide 17 antibody,
DEAD/HAsp-Glu-Ala-Asp/His) box polypeptide 1772kD) antibody.