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DDB1
DDB1 Antibody
DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development. Alternate names for DDB1 include damage-specific DNA-binding protein 1, UV-damaged DNA-binding factor, DDB p127, DDBa, UV-DDB1, xeroderma pigmentosum group E-complementing protein, XPCe, XPE-binding factor, XPE-BF, HBV-X-associated protein 1, XAP-1, and DDBA.
Product / Catalog #
Specifications
Price
DDB1 Antibody
A300-462A
Applications:
WB, IP
Reactivity:
Human, Mouse
Quantity:
0.1 ml (10 - 100 blots)
$280.00
Data Sheet
Add to Cart
DDB1 IHC Antibody
IHC-00134
Applications:
IHC
Reactivity:
Human, Mouse
Quantity:
0.1 ml (50 - 250 slides)
$360.00
Data Sheet
Add to Cart
DDB1 Blocking Peptide
BP300-462
Applications:
Blocks A300-462A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
ATM and ATR Signaling
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mTOR Signaling Pathway
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Xeroderma Pigmentosum
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Montgomery, TX 77356
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