DACH1 Antibody

Dachshund homolog 1 (Dach1) is a transcription factor that is involved in regulation of organogenesis. Dach1 seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Dach1 seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UI36].
    Product Specifications
    Catalog # Size Price
    DACH1 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 720 and 740
    A303-555A100 µl (0.2 mg/ml) $339Add to Cart
    A303-555A-M100 µl (10 blots) $229Add to Cart
    A303-555A-T20 µl (2 blots) $50Add to Cart
    DACH1 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 740 and 760
    A303-556A100 µl (0.2 mg/ml) $339Add to Cart
    A303-556A-M100 µl (10 blots) $229Add to Cart
    A303-556A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A303-555A and A303-556A
    A311-308A1 Pack $472Add to Cart

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