Cyclin T1 Antibody

Cyclin T1 is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, Cyclin T1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA) [taken from the Universal Protein Resource (UniProt)].
    Product Specifications
    Catalog # Size Price
    Cyclin T1 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 250 and 300
    A303-496A100 µl (0.2 mg/ml) $339Add to Cart
    A303-496A-M100 µl (10 blots) $229Add to Cart
    A303-496A-T20 µl (2 blots) $50Add to Cart
    Cyclin T1 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 625 and 675
    A303-499A100 µl (0.2 mg/ml) $339Add to Cart
    A303-499A-M100 µl (10 blots) $229Add to Cart
    A303-499A-T20 µl (2 blots) $50Add to Cart

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