Cyclin L2 Antibody

Cyclin L2 is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression and transcription. The hallmark characteristic of cyclins is the periodicity of their expression and activity that is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin L2 is part of a group of cyclins that are involved in transcriptional regulation at the level of RNA transcription, initiation, elongation, and RNA processing. The transcriptional regulating cyclins include cyclin C, H, K, L1, L2, T1, and T2 which associate with CDK7, -8, -9, -10 and -12. Cyclin L2 associates with CDK11 and RNA polymerase II and co-localizes with splicing factors and is implicated to play a role in pre-mRNA splicing.
    Product Specifications
    Catalog # Size Price
    Cyclin L2 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 275 and 325
    A301-676A100 µl (1 mg/ml) $339Add to Cart
    A301-676A-T10 µl (1 mg/ml) $50Add to Cart
    Cyclin L2 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 470 and 520
    A301-677A100 µl (0.2 mg/ml) $339Add to Cart
    A301-677A-M100 µl (10 blots) $229Add to Cart
    A301-677A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A301-676A and A301-677A
    A310-594A1 Pack $472Add to Cart

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