CrkRS Antibody

CrkRS (Cdc2-related kinase, arginine/serine-rich) is a Cdc-2 related kinase that contains an arginine- and serine-rich (SR) domain and has recently been reported to interact with cyclin L1 and L2. Since it has been discovered that CrkRs pairs with a cyclin partner, it has also been given the name CDK12. CrkRs localizes to nuclear speckles and immunoprecipitates with RNA polymerse II and the SF2/ASF splicing factor and is proposed to play a role in the regulation of alternative splicing.

Alternative names for CrkRS Antibody include cell division cycle 2-related protein kinase 7 antibody, CDC2-related protein kinase 7 antibody, CRKRS antibody, CRK7 antibody, KIAA0904 antibody.