Cbl-b Antibody

Cbl-b is an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Cbl-b negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q13191].

Alternative names for Cbl-b Antibody include E3 ubiquitin-protein ligase CBL-B antibody, casitas B-lineage lymphoma proto-oncogene b antibody, RING finger protein 56 antibody, SH3-binding protein CBL-B antibody, signal transduction protein CBL-B antibody, Cas-Br-M (murine) ecotropic retroviral transforming sequence b antibody, RNF56 antibody, CBLB antibody.