CSTF2T/TauCSTF64 Antibody

CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3’-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously; however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
    Product Specifications
    Catalog # Size Price
    CSTF2T/TauCSTF64 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 225 and 275
    A301-486A100 µl (1 mg/ml) $339Add to Cart
    A301-486A-T10 µl (1 mg/ml) $50Add to Cart
    CSTF2T/TauCSTF64 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 566 and 616
    A301-487A100 µl (1 mg/ml) $339Add to Cart
    A301-487A-M100 µl (10 blots) $229Add to Cart
    A301-487A-T20 µl (2 blots) $50Add to Cart

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