CSN5 Antibody

CSN5 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN also possesses kinase activity. CSN5 has been identified as the subunit that functions to remove Nedd8, an ubiquitin-like modifier, from cullin-based E3-ubiquitin ligases. CSN5 also functions as a coactivator of nuclear receptors. COP9 signalsome complex subunit 5, signalsome subunit 5, SGN5, jun activation domain-protein 1, COPS5, JAB1, MOV-34, MGC3149.
    Product Specifications
    Catalog # Size Price
    CSN5 AntibodyReactivity: Human, Mouse
    Applications: WB, IHC-P, IF
    Immunogen: Between 175 and 225
    A300-014A100 µl (1 mg/ml) $339Add to Cart
    A300-014A-M100 µl (10 blots) $229Add to Cart
    A300-014A-T20 µl (2 blots) $50Add to Cart
    CSN5 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 175 and 225
    IHC-00362100 µl (50+ slides) $360Add to Cart
    IHC-00362-T10 µl (5+ slides) $50Add to Cart

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