CSP1/TRAP220 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15648].
Alternative names for
CRSP1/TRAP220 Antibody include peroxisome proliferator-activated receptor –binding protein antibody, PBP antibody, PPAR-binding protein antibody, thyroid hormone receptor-associated protein complex 22 kDa component antibody, Trap220 antibody, thyroid receptor-interacting protein 2 antibody, TRIP-2 antibody, p53 regulatory protein RB18A antibody, vitamin D receptor-interacting protein complex component DRIP205 antibody, activator-recruited cofactor 205 kDa component antibody, ARC205 antibody, PPARB antibody, ARC205 antibody, DRIP205 antibody, PPARGBP antibody, MGC71488 antibody.