CRM1 Antibody

Chromosome region maintenance 1 protein homolog (CRM1) is the Ran-GTP-binding nuclear export receptor for proteins bearing a leucine rich nuclear export signal and RNAs. CRM1 also possesses a mitotic function as it localizes to kinetochores, and with Ran-GTP, recruits Ran-GTPase-activating protein (Ran-GAP1) and Ran-binding protein (Ran-BP2) for proper mitotic spindle assembly and chromosome segregation. Additionally, CRM1 is suggested to function as a loading dock of various cell cycle and checkpoint factors such as cyclins, Cdks, p53 and BRCA1, to regulate proper chromosome duplication and genomic stability.
    Product Specifications
    Catalog # Size Price
    CRM1 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 1025 and C-term
    A300-469A100 µl (1 mg/ml) $339Add to Cart
    A300-469A-M100 µl (10 blots) $229Add to Cart
    A300-469A-T20 µl (2 blots) $50Add to Cart
    CRM1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 375 and 425
    A300-490A100 µl (1 mg/ml) $339Add to Cart
    A300-490A-T10 µl (1 mg/ml) $50Add to Cart
    CRM1 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 1025 and C-term
    IHC-00139100 µl (50+ slides) $360Add to Cart
    IHC-00139-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, IHC-P, IF, PLA
    Reactivity: Human, Mouse
    Includes: 1 each of A300-490A and A300-469A
    A310-133A1 Pack $472Add to Cart

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