CPSF160 Antibody

CPSF160/CPSF1 (cleavage and polyadenylation specific factor 1, 160 kDa subunit) is a subunit of the cleavage and polyadenylation specificity factor (CPSF) involved in mammalian mRNA 3’-end processing. CPSF, along with CstF (cleavage and stimulation factor), is critical for the recognition of cis-acting sequence elements on the pre-mRNA that dictate the site of cleavage and subsequent polyadenylation. CPSF exists as a complex of four proteins that includes CPSF160, CPSF100, CPSF73, and CPSF30. CPSF160 is responsible for recognizing the (AAUAAA) poly (A) signal for cleavage and polyadenylation.
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