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COP1/RFWD2
COP1/RFWD2 Antibody
Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities. Alternate identifiers for COP1 include E3 ubiquitin-protein ligase RFWD2, RING finger and WD repeat domain protein 2, constitutive photomorphogenesis protein 1 homolog, hCOP1, RING finger protein 200, RFWD2, COP1, RNF200, FLJ10416, and RP11-318C24.3.
Product / Catalog #
Specifications
Price
COP1/RFWD2 Antibody
A300-894A
Applications:
WB, IP
Reactivity:
Human, Mouse
Quantity:
0.1 ml (20 - 100 blots)
$280.00
Data Sheet
Add to Cart
COP1/RFWD2 Antibody
A300-895A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
COP1/RFWD2 Antibody
A300-896A
Applications:
IP
Reactivity:
Human, Mouse
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
COP1/RFWD2 Antibody AbVantage™ Pack
A310-285A
Applications:
WB, IP
Reactivity:
Human, Mouse
Quantity:
1 each of A300-894A, A300-895A and A300-896A
$585.00
Data Sheet
Add to Cart
COP1/RFWD2 Blocking Peptide
BP300-894
Applications:
Blocks A300-894A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
COP1/RFWD2 Blocking Peptide
BP300-895
Applications:
Blocks A300-895A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
COP1/RFWD2 Blocking Peptide
BP300-896
Applications:
Blocks A300-896A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
ATM and ATR Signaling
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Montgomery, TX 77356
Phone: 1-800-338-9579
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