COP1/RFWD2 Antibody

Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities.
Antibodies Manufactured onclick Site
We Make Every Antibody
We Sell.

Please note that Cookies and JavaScript are required for you to view this website.

Check if you have Cookies and JavaScript enabled in your browser