CIZ Antibody

CAS-interacting zinc finger protein (CIZ) is also known as nuclear matrix protein 4 (NMP4) and the gene name zinc finger protein 384 (ZNF384). CIZ is a C2H2-type zinc finger protein, which may function as a transcription factor. CIZ appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling [taken from NCBI Entrez Gene (Gene ID: 171017)].
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