CHD8 Antibody

CHD8 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD8 has been reported to interact with duplin, a protein involved in the wnt signaling pathway, and CTCF, a protein involved in heterochromatin formation.

Alternative names for CHD8 Antibody include chromodomain-helicase-DNA-binding protein 8 antibody, ATP-dependent helicase CHD8 antibody, helicase with SNF2 domain 1 antibody, HELSNF1 antibody, KIAA1564 antibody.