CHD7 Antibody

CHD7 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD7 is implicated to play a role in development. Mutations in CHD7 are associated with CHARGE syndrome, a multi-symptom syndrome characterized by congenital anomalies and malformations of the heart, inner ear, retina, and palate.

Alternative names for CHD7 Antibody include chromodomain-helicase-DNA-binding protein 7 antibody, ATP-dependent helicase CHD7 antibody, KIAA1416 antibody, IS3 antibody, FLJ20357 antibody, FLJ20361 antibody.