CDK5RAP3 Antibody

CDK5RAP3 (CDK5 regulatory subunit-associated protein 3) was identified as a protein that associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development; however CDK5RAP3 appears to be widely expressed in human tissues. CDK5RAP3 appears to exhibit functions that extend beyond its association with Cdk5. CDK5RAP3 is involved in modulating the G2/M DNA damage checkpoint and can associate with and regulate the Cdk1-cyclin B1 complex. CDK5RAP3 has also been demonstrated to interact with and regulate the tumor suppressor ARF (alternative reading frame) to further play a role in cell cycle progression.
    Product Specifications
    Catalog # Size Price
    CDK5RAP3 AntibodyReactivity: Human
    Applications: WB
    Immunogen: Between 275 and 325
    A300-870A100 µl (0.2 mg/ml) $339Add to Cart
    A300-870A-M100 µl (10 blots) $229Add to Cart
    A300-870A-T20 µl (2 blots) $50Add to Cart
    CDK5RAP3 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 450 and C-term
    A300-871A100 µl (1 mg/ml) $339Add to Cart
    A300-871A-M100 µl (10 blots) $229Add to Cart
    A300-871A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A300-870A and A300-871A
    A310-274A1 Pack $472Add to Cart

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