CDCA3/TOME1 Antibody

CDCA3/TOME1 is an F-box protein and is part of the SCF complex, an ubiquitin ligase complex that promotes degradation of the mitosis-inhibitory kinase, wee1. CDCA3/TOME1 expression is cell cycle regulated by cis-promoter elements and activated at the G2/M phase. CDCA3/TOME1 levels are also regulated at the protein level via degradation by the APC (anaphase-promoting complex) during G1.

Alternative names for CDCA3/TOME1 Antibody include cell division cycle-associated protein 3 antibody, trigger of mitotic entry protein 1 antibody, TOME-1 antibody, gene-rich cluster protein C8 antibody, GRCC8 antibody.