CDC20 Antibody

CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.
    Product Specifications
    Catalog # Size Price
    CDC20 AntibodyReactivity: Human, Mouse
    Applications: IP, IHC-P, IF
    Immunogen: Between 50 and 100
    A301-179A100 µl (1 mg/ml) $339Add to Cart
    A301-179A-T10 µl (1 mg/ml) $50Add to Cart
    CDC20 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 449 and 499
    A301-180A100 µl (0.2 mg/ml) $339Add to Cart
    A301-180A-M100 µl (10 blots) $229Add to Cart
    A301-180A-T20 µl (2 blots) $50Add to Cart

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