CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.
Alternative names for
CDC20 Antibody include p55CDC antibody,
Cell division cycle protein 20 homolog antibody,
cell division cycle 20 antibody,
cell division cycle protein 20 homolog antibody,
cell division cycle 20 homolog antibody,
CDC20 cell division cycle 20 homolog antibody.