CBF-beta (isoform 2) Antibody

Core-binding factor subunit beta (CBF-beta) is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13951].
    Product Specifications
    Catalog # Size Price
    CBF-beta (isoform 2) AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 166 and 182
    A303-548A100 µl (1 mg/ml) $339Add to Cart
    A303-548A-M100 µl (10 blots) $229Add to Cart
    A303-548A-T20 µl (2 blots) $50Add to Cart

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