CAP-H Antibody

CAP-H is a subunit of the heteropentameric condensin I complex. Condensin participates in the condensation of chromosomes during cell division by facilitating positive DNA supercoiling and knotting by topoisomerase I and II and proper segregation of sister chromatids. CAP-H is a non-SMC regulatory subunit of the condensin complex that may have an important role in condensin’s ability to maintain structural integrity of centromeric heterochromatin during mitosis.
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