CAND1 Antibody

Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q86VP6].

Alternative names for CAND1 Antibody include cullin-associated and neddylation-dissociated protein 1 antibody, TBP-interacting protein of 120 kDa A antibody, p120 CAND1 antibody, TIP120 antibody, TIP120A antibody, KIAA0829 antibody.