CAND1 Antibody

Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q86VP6].
    Product Specifications
    Catalog # Size Price
    CAND1  AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 600 and 650
    A302-900A100 µl (1 mg/ml) $339Add to Cart
    A302-900A-T10 µl (1 mg/ml) $50Add to Cart
    CAND1  AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 1180 and 1230
    A302-901A100 µl (1 mg/ml) $339Add to Cart
    A302-901A-M100 µl (10 blots) $229Add to Cart
    A302-901A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A302-900A and A302-901A
    A311-070A1 Pack $472Add to Cart

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