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By Research Area / Cell Cycle / BubR1

BubR1 Antibody

BubR1 is cell cycle checkpoint kinase and component of the spindle checkpoint machinery. BubR1 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. BubR1 is part of the mitotic checkpoint complex that also includes Bub3, Mad2, and Cdc20. In this trimer BubR1 functions to inhibit the anaphase promoting complex (APC) that promotes chromosome segregation. BubR1 is suggested to be a paralog of Bub1. BubR1 is also known as mitotic checkpoint serine/threonine-protein kinase BUB1 beta, hBUBR1, MAD3/BUB1-related protein kinase, mitotic checkpoint kinase MAD3L, SSK, SSK1, Bub1A, MAD3L, and BUB1beta.

Product / Catalog #	Specifications	Price
BubR1 Antibody A300-386A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (50 - 150 blots)	$310.00 Data Sheet Add to Cart
BubR1 Antibody A300-995A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (20 - 100 blots)	$310.00 Data Sheet Add to Cart
BubR1 Blocking Peptide BP300-386	Applications: Blocks A300-386A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart
BubR1 Blocking Peptide BP300-995	Applications: Blocks A300-995A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart

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